HIPEC Protocols

Regimen 1.
Mitomycin C. Dose HIPEC is 30 mg / m2 in patients with an increased risk of perioperative dose was reduced to half. Upon reaching 41-42 degrees add ½ of the calculated dose during 30 minutes added on ¼. Total HIPEC 90 minutes.
The temperature of the lavage solution should not exceed 43 degrees Celsius.


Regimen  2.
Cisplatin. Dose of 50 mg / m2 in conmbinatsiya doxorubicin 15 mg / m2. Upon reaching 41-42 degrees Tsezliy is added to the dose calculated for 30 minutes.
The temperature of the lavage solution should not exceed 43 degrees Celsius.


In both modes of lavage solution is 1.5% destroza peritoneal dialysis solution.
An additional 10 minutes before the start of HIHT be applicated intravenous 5-Flourouratsil 400mg / m2.